Intelligent Enzyme Intelligence: Enzyme Sources Guide

November 4, 2013

Tweet Ryan and I have just created the Enzyme Sources Guide, a publication we hope will be an indispensable resource covering the enzyme industry. With 461 pages containing profiles of more than 200 enzyme producers, developers, and suppliers around the world, the Enzyme Sources Guide is the most comprehensive compendium available covering the players in the enzyme […]

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Vitamins for Ethanol?

October 31, 2013

Tweet Calling it a “vitamin shot” for ethanol production, exactly one year ago Novozymes launched Avantec, a new enzyme product that raised ethanol yields from corn. The enzyme raises the amount of ethanol produced from corn starch by 2.5%. That may not sound like much, but with more than 13 billion gallons of ethanol produced, that […]

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Recent Biocatalysis Publications and Patents, Halogenases, and More

October 22, 2013

Tweet The latest Mainstream Biocatalysis Newsletter went out this morning. In addition to the latest publications and patent applications, this issue features halogenases in the enzyme profile section and Finnish enzyme company Metgen Oy in the company profile.  Wnat to know more? Sign up in the sign-up box to the right. To view the most […]

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Nobel Prize in Chemistry: Implications for Enzymes and Biocatalysis

October 9, 2013

Tweet Congratulations to Martin Karplus, Michael Levitt and Arieh Warshel on receiving the honor of the Nobel Prize in Chemistry this year. Their pioneering work on computer modeling of  chemical processes is discussed mostly in terms of small molecules, but it has also led to breakthroughs in modeling protein-small molecule interactions, and thus drug discovery and biocatalysis. […]

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New Enzyme and Biocatalysis Newsletter Out Today

October 8, 2013

Tweet If you already signed up for the Mainstream Biocatalysis Newsletter, you received today the latest news, enzyme and company information, patents and publications direct to your in-box. If you didn’t get you copy this morning, just use the sign-up box to the right to be added to our mailing list. To see today’s issue of […]

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New Enzyme Word for Today: Ortholog

October 6, 2013

Tweet The effort to understand the functions of new genes relies heavily on using homology to identify genes with similar functions.  There is even a word to describe enzymes that perform the same task in other organisms: orthologs. Although this word is new one for me, it was actually coined in 1970 by Walter Fitch (Fitch […]

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Verenium Breaking News: BASF to Acquire Verenium

September 20, 2013

Tweet BASF Corporation, has entered into an agreement to commence a cash tender offer for all of the outstanding shares of common stock of the biotechnology company Verenium Corporation (NASDAQ: VRNM) for US$4.00 per share.

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Most Important Enzyme in the World

September 18, 2013

Tweet I enjoy superlatives, and today’s post features an enzyme that fits neatly into that category: the world’s most important enzyme. The selected enzyme may generate some disagreements—always welcome.  My candidate for the most important enzyme in the world is ribulose-1,5-bisphophate carboxylase/oxygenase (EC 4.1.1.39), more commonly referred to as rubisco. Why is rubisco the world’s […]

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What Is the Smallest Enzyme?

September 12, 2013

Tweet How small can an enzyme be? The leading candidate that I can find is 4-Oxalocrotonate tautomerase (EC 5.3.2.6): just 62 amino acids. At least that is the mass of one subunit. Un its physiologically-active form the enzyme is a homo-hexamer. Does that mean it is really a 372 amino acid enzyme? What is your candidate […]

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Overcoming Pulping Recalcitrance: The Path to Cheaper Biofuels?

September 11, 2013

Tweet From Scientific American: a new enzyme that may help bring down the cost of cellulosic biofuels in the future. Caffeoyl shikimate esterase (CSE) is an enzyme involved in the formation of lignin. Shutting it off at the right time, for example, right before harvest, can facilitate the extraction of cellulose from the lignin. In […]

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